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Homocysteine

$92.00
SHIPPING RESTRICTIONS:
Please note that lab kits cannot be shipped to
New York, Alaska, Hawaii, or internationally.
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SKU:
LHomo
Homocysteine is an intermediate in the synthesis of cysteine from methionine, via cystathionine. Deficiency of vitamins B12, B6 and/or folic acid can affect the enzyme pathways associated in the formation of cysteine, resulting in an elevated homocysteine in the blood. Numerous studies have shown an association between elevated levels of blood homocysteine and various vascular and cardio-vascular diseases. It is thought that homocysteine may act as a molecular abrasive damaging the inner layer of blood vessels causing an atherosclerotic lesion. Increased levels of homocysteine have been associated with advanced age, hypothyroidism, impaired renal function, and SLE. Medications known to elevate homocysteine are nicotinic acid, L-DOPA, theophylline and methotrexate.
 

REFERENCES:

  • Clarke R., Daly L., Robinson K., et. al. Hyperhomocysteine: An independent risk factor for vascular disease. N Engl J Med, 1991, 324:1149-55.
  • Caffaneo, M. Hyperhomocysteine, Atherosclerosis and Thrombosis. Thromb Haemost, 1998, 81:165-76.
  • Herman, W. The importance of hyperhomocysteinemia as a risk factor for diseases: an overview. Clin Chem Lab Med, 2001, 39(8):666-74.
 
CPT CODE:
82131
COLLECTION CONTAINER:
SST or red-stopper tube
STATE & SHIPPING RESTRICTIONS:
We cannot ship lab kits to NY, AK, HI, or international
MINIMUM VOLUME:
0.5 mL
NORMAL VALUES:
Reference values established in our laboratory are 5 to 15 umol/L
PATIENT PREP:
None
PROCESS METHOD:
The methodology for homocysteine is by Fluorescence Polarization Immuno Assay (FPIA).
PROCESS TIME:
5 to 7 business days
REJECTION CAUSES:
Gross Hemolysis
SPECIMEN VOLUME:
1 mL serum
TRANSPORT CONTAINER:
Plastic transport tube
TRANSPORT INSTRUCTIONS:
Refrigerate or freeze