Cal/Mag/Zinc Complex with Vitamin D, 240 Capsules

Vitamin D3 stimulates absorption of calcium from the gut. Vitamin D deficiency has been associated with many forms of cardiovascular disease. Many factors, including lack of exposure to sunlight, sunscreen use, living at higher latitudes, and dark skin pigmentation, can result in low serum vitamin D levels.

Calcium is required for the critical metabolic functions of vascular contraction and vasodilation, muscle function, nerve transmission, intracellular signaling and hormonal secretion. Calcium is also necessary for maintenance of bone strength. When calcium intake is inadequate, the body uses bone as a reservoir to maintain serum calcium levels. Osteoporosis occurs when the creation of new bone doesn't keep up with the removal of old bone.

Magnesium is involved in over 300 biochemical reactions in the body, including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It maintains regular heartbeat, and has been found to reduce cardiovascular disease risk. Magnesium is essential for the absorption of calcium, acts on crystal formation in bone cells, and impacts the activity of parathyroid hormone, a regulator of calcium homeostasis. 60% of the body's magnesium is stored in bones. Magnesium deficiency results in lower BMD as magnesium is pulled out of bone for other biological functions.

Zinc has been demonstrated to have a stimulatory effect on bone formation and mineralization and to inhibit bone resorption. Zinc appears to have protective effects for cardiac health. Zinc deficiency has been linked to many forms of heart disease, and replenishing zinc has been shown to improve cardiac function.

Boron plays a role in the formation of steroid hormones such as estradiol, supporting bone health by prevention of demineralization. Boron also increases the effectiveness of vitamin D.