Product Code: LRbcCu
Copper is a trace mineral and is associated with a number of metalloproteins, whose major functions involve oxidation-reductions in many important enzymes. It is also associated with iron in red blood cell formation, energy release, and is important in the synthesis of melanin, nerve coverings, collagen and elastin.
Copper is transported in the blood attached to ceruloplasmin.
Deficiency symptoms of copper may include anemia, fatigue, fragile bones and blood vessels, and lower disease resistance. Copper toxicity results in nausea, vomiting, epigastric burning and diarrhea. Classic conditions associated with copper deficiency are Menke's syndrome and Wilson's disease. Estrogens (birth control pill or pregnancy) may cause an increase in blood copper by increasing the production of ceruloplasmin.
Copper is widely distributed and may be found in shellfish, liver, cherries, nuts cocoa, gelatin, and from copper water pipes. With all minerals, the RDA may be different for children and pregnant or lactating women. A normal safe daily intake is 1.5 to 3.0 mg/day.
Copper intake must be proportional with zinc and iron, if not, an imbalance of copper may occur.
Doctors who wish to order kits, please call our lab directly to set up an account before ordering. 316-684-7784
Process time: 5 to 7 business days
Process method: The methodology is by atomic absorption/ICP.
CPT code: 82525
Special instructions: None
Patient prep: None
Specimen volume: 0.5 mL Heparin RBC, washed 1x
Minimum volume: 0.05 mL
Collection container: Heparin tube
Transport container: Metal-free plastic transport tube
Transport instructions: Refrigerate or freeze
Collection instructions: Click here for PDF
Normal values: RBC = 46 to 79 ug/dL
Reference one: Vulpe, C.D., Packman, S.: Cellular copper transport. Annu. Rev. Nutr., 15:293-322, 1995.
Reference two: Chaudhri, G.P., Hannaker, P.: Reliability of the ICP-AES for trace elements studies of biological materials. Biol. Trace Elem. Res., 13:417, 1987.
Reference three: Tietz Textbook of Clinical Chemistry, 3rd Edition, 1999, Saunders Company, Chapter 30.
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