Pyrroles, Urine (Pyrroluria, Kryptopyrrole, Mauve Factor)
Product Code: LPyr
Price: $79.00
Test Description
Pyrroles, Urine (Pyrroluria, Kryptopyrrole, Mauve Factor)
CALL TO ORDER: 800-447-7276 x1385
Test Details
Process time: 5 to 7 business days
CPT code: 84999
Special instructions: None
Rejection causes: Ascorbic acid not used to maintain specimen stability
Collection Instructions
Patient prep: (1) If first time testing for pyrroles, discontinue taking any B6 or Zinc one week prior to collecting specimen. (2) If under treatment for pyrroluria, continue taking vitamin B6 and Zinc
Specimen volume: Approximately 8 mL urine added to 500mg of ascorbic acid. Stable at least 1 month if kept frozen.
Minimum volume: 2 mL
Collection container: Clean container
Transport container: Amber plastic transport tube or protected from light
Transport instructions: Freeze
Results
Normal values: Normal reference range is less than 20 ug/dL. A "borderline" value is between 10 to 20 ug/dL.
References
Reference one: Irving DG: Apparent non-indolic ehrlich-positive substances related to mental illness. J Neuropsychiat, 1961;2:292-305.
Reference two: Hoffer A, Mahon M: The presence of unidentified substances in the urine of psychiatric patients. J Neuropsychiat, 1961;2:331-397.
Reference three: Irvine DG, Bayne W, et al: Identification of kryptopyrrole in human urine and its relationship to psychosis. Nature, 1969;224:811-813.
Reference four: Pfeiffer CC, Lliev V: Pyrroluria, urinary mauve factor, causes double deficiency of B6 and zinc in schizophrenics. Fed Proc, 1973;32:276.
Reference five: Jackson JA, Riordan HD, Neathery S: Vitamins, blood lead and urine pyrroles in Down Syndrome patients. Amer Clin Lab, 1990:Jan- Feb:8-9.
Reference six: Jackson JA, Riordan HD, Neathery S, Riordan N: Urinary pyrroles in health and disease. J Orthomol Med, 1997: 12;2:96-98.
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