Prostate-Specific Antigen (PSA)

Prostate-Specific Antigen (PSA)

PSA is a secretion of prostate epithelium and is also produced by prostate cancer cells. It is a glycoprotein with protease activity. It can be used with digital rectal examination (DRE), and ultrasonography to detect prostate cancer. PSA may be elevated in prostate cancer or BPH (benign prostate hypertrophy), prostates, urinary retention, urethral instrumentation, needle biopsy, etc. Elevated PSA can only suggest the presence of prostate cancer. Prostate biopsy is is required for diagnosis of cancer. PSA testing can have significant value in monitoring patients with prostate cancer.

Specimen is serum.

Doctors who wish to order kits, please call our lab directly to set up an account before ordering. 316-684-7784

Process time: 5 to 7 business days

Process method: The methodology is by Microparticle Enzyme Immunoassay (MEIA) technology.

CPT code: 84153

Special instructions: None

Rejection causes: Gross Hemolysis

Patient prep: None

Specimen volume: 1 mL serum

Minimum volume: 0.5 mL

Collection container: SST or red-stopper tube

Transport container: Plastic transport tube

Transport instructions: Freeze

Collection instructions: Click here for PDF

Normal values: The normal range established in our laboratory is 0.0 - 4.0 ng/mL.

Reference one: Barak M, Mecz Y., Lurie, A., et al. Evaluation of PSA as a Marker for Adenocarcinoma of the Prostate, J Clin Lab Med, 1989, 113(1):598-603.

Reference two: American Urological Association- Early Detection of Prostate Cancer Policy Statement. Board of Directors Minutes, 1992.

Reference three: Gerber, G.S., Chodak, G.W. Routine Screening for Cancer of the Prostate (Review). J of Nat Ca Ins, 1991;83:329.