Product Code: LDhea
DHEA is produced in the adrenal cortex from pregnenolone. The half-life of DHEA is only about 30 minutes while the sulfated form lasts much longer. About 95% of DHEA is in the DHEA-S form. DHEA-S is used to produce estrogens and androgens in the adrenal glands, ovaries and testes. DHEA reaches the highest level at about age 25. By the age of 80, the DHEA level is only about 20% of the younger age. DHEA is involved in many health conditions including obesity, arthritis, lupus, hypertension, cancer, stress, atherosclerosis, Cushing's syndrome, sleep disorders, dementia and Alzheimer's disease.
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Process time: 5 to 7 business days
Process method: The methodology is by RIA.
CPT code: 82627
Special instructions: None
Rejection causes: Gross Hemolysis
Patient prep: None
Specimen volume: 0.5 mL serum
Minimum volume: 0.1 mL
Collection container: SST or red-stopper tube
Transport container: Plastic transport tube
Transport instructions: Refrigerate or freeze
Collection instructions: Click here for PDF
Normal values: The normal range established in our laboratory for DHEA-S is by age and gender of the individual. This will be reported on the patientÆs report.
Reference one: Rosenfield RS, Rosenberg BJ, et al. 24-hour secretory pattern of DHEA and DHEA-S. J Clin Endocrin Metab, 1975, 40:850-855.
Reference two: Rosenfield RS, Hellman L, Gallager TF. Metabolism and interconversion of DHEA and DHEA-S. J Clin Endocrin Metab, 1972, 35:187-193.
Reference three: Namiki M. Aged people and stress. Jap J Geriatrics, 1994, 31:85-95.
Reference four: Nestler JE, Clore JN, Blackard WG. DHEA: the "missing link" between hyperinsulinism and atherosclerosis? FASEBJ, 1992, 6(12), 3073-3075.
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