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Copper, Serum
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    Copper, Serum

    Product Code: LCopB

    Price: $105.00

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    Test Description

    Copper, Serum

    Copper is a trace mineral and is associated with a number of metalloproteins, whose major functions involve oxidation-reductions in many important enzymes. It is also associated with iron in red blood cell formation, energy release, and is important in the synthesis of melanin, nerve coverings, collagen and elastin.

    Copper is transported in the blood attached to ceruloplasmin.

    Deficiency symptoms of copper may include anemia, fatigue, fragile bones and blood vessels, and lower disease resistance. Copper toxicity results in nausea, vomiting, epigastric burning and diarrhea. Classic conditions associated with copper deficiency are Menke's syndrome and Wilson's disease. Estrogens (birth control pill or pregnancy) may cause an increase in blood copper by increasing the production of ceruloplasmin.

    Copper is widely distributed and may be found in shellfish, liver, cherries, nuts cocoa, gelatin, and from copper water pipes. With all minerals, the RDA may be different for children and pregnant or lactating women. A normal safe daily intake is 1.5 to 3.0 mg/day.

    Copper intake must be proportional with zinc and iron, if not, an imbalance of copper may occur.

    Test Details

    Process time: 5 to 7 business days

    Process method: The methodology is by atomic absorption/ICP.

    CPT code: 82525

    Special instructions: None

    Rejection causes: Hemolysis

    Collection Instructions

    Patient prep: None

    Specimen volume: 0.5 mL serum

    Minimum volume: 0.05 mL

    Collection container: Trace element non-additive tube

    Transport container: Metal-free plastic transport tube

    Transport instructions: Refrigerate or freeze

    Collection instructions: Click here for PDF


    Normal values: Serum = 70 to 140 ug/dL


    Reference one: Vulpe, C.D., Packman, S.: Cellular copper transport. Annu. Rev. Nutr., 15:293-322, 1995.

    Reference two: Chaudhri, G.P., Hannaker, P.: Reliability of the ICP-AES for trace elements studies of biological materials. Biol. Trace Elem. Res., 13:417, 1987.

    Reference three: Tietz Textbook of Clinical Chemistry, 3rd Edition, 1999, Saunders Company, Chapter 30.

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